Scientists Flip an Alzheimer’s Risk Gene – and Reverse Key Hallmarks of the Disease

Yes, yes, yes!!

“The team designed a novel mouse model that lets researchers effectively “flip a switch,” converting the high-risk form of the gene (APOE4) into the protective version (APOE2) in adult animals. 

Carrying the APOE4 variant can raise a person’s likelihood of developing Alzheimer’s by as much as 15 times. In contrast, individuals with APOE2 generally face lower risk and show better cognitive health as they age. In the study, activating the gene switch specifically in astrocytes led to notable improvements.”

https://scitechdaily.com/scientists-flip-an-alzheimers-risk-gene-and-reverse-key-hallmarks-of-the-disease/