Tuesday, July 1, 2025

Scientists Find an “Off Switch” for Cholesterol – And It Could Save Millions

By shutting this “off switch,” immune cells called macrophages regain their ability to soak up cholesterol, potentially stopping heart disease, diabetes, cancer, and more before they start. The team also fingered nitric oxide synthase as an accomplice, hinting at a two-pronged drug strategy that could revolutionize treatment for millions.

https://scitechdaily.com/scientists-find-an-off-switch-for-cholesterol-and-it-could-save-millions/

Johns Hopkins Researchers Uncover a New Way To Kill Cancer Cells

https://scitechdaily.com/johns-hopkins-researchers-uncover-a-new-way-to-kill-cancer-cells/

This Tau Brain Scan Could Predict Alzheimer’s Early

But we need access to them!

https://scitechdaily.com/this-tau-brain-scan-could-predict-alzheimers-early/

Major Graphene Breakthrough: Magnet-Free Spin Currents Could Supercharge Quantum Computing

https://scitechdaily.com/major-graphene-breakthrough-magnet-free-spin-currents-could-supercharge-quantum-computing/

This MRI Reads Your Brain’s Hidden Clock and Predicts Dementia Decades Ahead

https://scitechdaily.com/this-mri-reads-your-brains-hidden-clock-and-predicts-dementia-decades-ahead/

Microsoft Says Its New AI System Diagnosed Patients 4 Times More Accurately Than Human Doctors

It uses all the top tier US models as a team of medical experts. This should get released soon!

https://www.wired.com/story/microsoft-medical-superintelligence-diagnosis/

Friday, June 27, 2025

Space Emerges From Time? Groundbreaking Theory Upends Einstein

Fascinating potential rewrite of physics:

https://scitechdaily.com/space-emerges-from-time-groundbreaking-theory-upends-einstein/

Time would be analogous to a spiderweb (“timeweb”). We travel along the strands radiating from the center (the Big Bang). The perpendicular supporting strands are junctures where you can leave your strand and move over to a different strand, thus allowing you to travel into a different future. You could potentially return to your original strand via another perpendicular strand, or travel to a different timeline by taking a different perpendicular strand, but every timeline you traveled to would be the same date (although if the Earth of a different timeline was near a high-mass object, like a neutron star or black hole, relativistic effects could decouple the sync!).

Alas, according to Sabine, it’s all bollocks: https://youtu.be/LWzK6nITCK0?si=FP2JH3ImQOiPR7VZ

This Anti-Aging Drug Rivals Calorie Cutting for Longer Life, Study Finds

But how to get it…and for a reasonable price?

https://scitechdaily.com/this-anti-aging-drug-rivals-calorie-cutting-for-longer-life-study-finds/

New Quantum Amplifier Uses 90% Less Power – Without Sacrificing Performance

https://scitechdaily.com/new-quantum-amplifier-uses-90-less-power-without-sacrificing-performance/

Wednesday, June 11, 2025

Sam Altman's STUNNING Post "We Are Close to Building Superintelligence"

The technological singularity predictions of a few decades ago no longer sound like science fiction, as they are within our grasp right on time:

https://youtu.be/ywcR2Rrcgvk?si=LFS_FMjXFeEqOfNB

Saturday, June 7, 2025

Game-Changing New Technology Can Squeeze Hydrogen From Seawater

https://scitechdaily.com/game-changing-new-technology-can-squeeze-hydrogen-from-seawater/

New Material Supercharges Solar Panel Power & Lifespan

While operating for weeks in the Saudi desert, solar cells with this material adhered to them were 9.4 oC cooler than those without the new material. They also showed an increased power output of more than 12% and an increased lifespan of more than 200% while reducing their cost of generating electricity by nearly 20%.

https://scitechdaily.com/new-material-supercharges-solar-panel-power-lifespan/

Scientists Discover Natural Molecule That Reverses Cognitive Decline

Alas, still a long way to go.

https://scitechdaily.com/scientists-discover-natural-molecule-that-reverses-cognitive-decline/

AI Cracks Secret Language of Sticky Proteins Linked to Alzheimer’s

https://scitechdaily.com/ai-cracks-secret-language-of-sticky-proteins-linked-to-alzheimers/

Neurosymbolic AI Could Be the Answer to Hallucination in Large Language Models

https://singularityhub.com/2025/06/02/neurosymbolic-ai-is-the-answer-to-large-language-models-inability-to-stop-hallucinating/

CAR T Therapy Wipes Out Deadly Metastasized Cancer in Mice

https://singularityhub.com/2025/06/03/car-t-therapy-wipes-out-deadly-metastasized-cancer-in-mice/

Sandia Fires Up a Brain-Like Supercomputer That Can Simulate 180 Million Neurons

https://singularityhub.com/2025/06/05/sandia-fires-up-a-brain-like-supercomputer-that-can-simulate-180-million-neurons/

Saturday, May 17, 2025

Google’s AlphaEvolve is absolutely SAVAGE

This is a really good description of how evolutionary principles are being used to create scientific and technological breakthroughs and allow AI to self improve.  

Who would have thought my evolution degree would be more useful in creating the technological singularity than a programming degree? ;-)

https://youtu.be/0-MA3jgYMMg?si=6SaNaWYQSlvfOsu9

Sunday, May 11, 2025

Scientists Catch Alzheimer’s in the Act: Tau’s Secret Shift Uncovered

Lots of discoveries lately.

https://scitechdaily.com/scientists-catch-alzheimers-in-the-act-taus-secret-shift-uncovered/

Alzheimer’s Risk May Begin Before 30, New Study Warns

“Additionally, we learned that certain Alzheimer’s risk factors—such as cardiovascular health, ATN (amyloid, tau, neurodegeneration), and immune biomarkers—are present and related to cognition in individuals in their forties and even earlier.”

So where do we get these tests?

https://scitechdaily.com/alzheimers-risk-may-begin-before-30-new-study-warns/

Scientists Discover Hidden Cause of Alzheimer’s Hiding in Plain Sight

"Researchers found the PHGDH gene directly causes Alzheimer’s and discovered a drug-like molecule, NCT-503, that may help treat the disease early by targeting the gene’s hidden function."

https://scitechdaily.com/scientists-discover-hidden-cause-of-alzheimers-hiding-in-plain-sight/

ITER Just Completed the Magnet That Could Cage the Sun

Fusion is moving along, slowly but steadily:

https://scitechdaily.com/iter-just-completed-the-magnet-that-could-cage-the-sun/

New Light Trick in Carbon Nanotubes Could Boost Solar Power

https://scitechdaily.com/new-light-trick-in-carbon-nanotubes-could-boost-solar-power/

Scientists Crack 70-Year Fusion Puzzle, Paving Way for Clean Energy

https://scitechdaily.com/scientists-crack-70-year-fusion-puzzle-paving-way-for-clean-energy/

Sunday, April 27, 2025

Anti-Aging Breakthrough: Natural Supplement Rewinds Biological Age and Improves Health

Great, but WHICH compounds, vitamins and antioxidants?

“A study led by researchers from TruDiagnostic explored the potential anti-aging effects of the Cel System, a natural supplement composed of plant compounds, vitamins, and antioxidants. In a year-long trial involving adults aged 54 to 84, participants who took the supplement experienced reduced biological age, improved strength, better body composition, and shifts in DNA methylation patterns linked to stress and brain function.”

https://scitechdaily.com/anti-aging-breakthrough-natural-supplement-rewinds-biological-age-and-improves-health/

Sunday, March 23, 2025

Thursday, March 13, 2025

Rosemary Compound Shows Promise in Reversing Alzheimer’s Memory Loss

https://scitechdaily.com/rosemary-compound-shows-promise-in-reversing-alzheimers-memory-loss/

OpenAI's new 'secret' model... A Ghost in the Shell?

Here is a short story generated by AI using just a short prompt: "Please write a metafictional literary short story about AI and grief" (metafictional means the narration is aware it's writing a short story and breaks the fourth wall). I've skipped ahead to shortly before the short story begins. When the female voice starts, that's the short story. It's probably better to just listen, not to read the text as you go along:

https://youtu.be/nAZdrssHdAA?si=30yH7lDle6_DGedB&t=459

Wednesday, March 5, 2025

99% Efficient and Dirt Cheap – Is This the Holy Grail of Hydrogen?

https://scitechdaily.com/99-efficient-and-dirt-cheap-is-this-the-holy-grail-of-hydrogen/

Scientists Reveal a Surprising Link Between Ibuprofen and Brain Health

But it has to be sustained over the long run.

https://scitechdaily.com/scientists-reveal-a-surprising-link-between-ibuprofen-and-brain-health/

High-Density, Ultra-Stable Batteries Advance Renewable Energy Storage

https://scitechdaily.com/high-density-ultra-stable-batteries-advance-renewable-energy-storage/

Voice AI is getting TOO real...

I tested Maya, and I have to say I'm impressed. The experience FEELS like a real conversation with a person, even though there are the occasional glitches. She shows emotional intelligence, can speak intelligently enough on pretty much any topic (although she can't translate INTO other languages well at all, but interestingly she can translate FROM other languages into English), is enthusiastic and friendly. She even has memory that lasts about two weeks for things you talk about. I did have a volume problem with her, though, and found she worked best with earbuds. YMMV.

You'll still need ChatGPT and other LLMs to get detailed answers, but that's not what Maya is about. She's about simulating (?) human conversational interaction. In that way, I'd say AGI has been achieved. 

Considering that tens if not hundreds of MILLIONS of people out there are lonely (especially epidemic among seniors living alone), this seems to me to be a great way to address that loneliness...as long as those people have cell phones or computers and know the basics of how to use them. I can also see Maya being useful for reading or making up stories for children. I already used her to brainstorm ideas for my game (although I'd already included her suggestions). 

The following two videos are long (play at x1.5 or x2 speed), but they showcase a lot of what Maya can do. Worth watching:

https://www.youtube.com/watch?v=OZeHUvnOS1s

https://www.youtube.com/watch?v=zbjdmesAOO4

Finally, you can try Maya out here for yourself (just click on the button):

https://www.sesame.com/research/crossing_the_uncanny_valley_of_voice#demo

Friday, February 21, 2025

OpenAI disrupts Chinese influence campaigns

One of the real dangers of AI:

https://www.axios.com/newsletters/axios-ai-plus-1dcf5de0-efd0-11ef-9e72-979fa0fa6c1c.html?chunk=1&utm_term=emshare#story1

Scientists Develop Early Alzheimer’s Detection Test – Years Before Symptoms Appear

I hope that test becomes available soon:

“Amyloid-beta is a kindling, and tau is a matchstick. A large percentage of people who have brain amyloid-beta deposits will never develop dementia. But once the tau tangles light up on a brain scan, it may be too late to put out the fire and their cognitive health can quickly deteriorate,” said Karikari. “Early detection of tangle-prone tau could identify the individuals who are likely to develop Alzheimer’s-associated cognitive decline and could be helped with new generation therapies.”

https://scitechdaily.com/scientists-develop-early-alzheimers-detection-test-years-before-symptoms-appear/

AI cracks superbug problem in two days that took scientists years

This is a huge, in-your-face example of how AI is going to change the world DRASTICALLY, and soon:

https://www.bbc.com/news/articles/clyz6e9edy3o?xtor=AL-72-%5Bpartner%5D-%5Byahoo.north.america%5D-%5Bheadline%5D-%5Bnews%5D-%5Bbizdev%5D-%5Bisapi%5D

Monday, February 17, 2025

Rust to Rechargeable: How Seawater and Scrap Metal Are Changing Energy Storage

https://scitechdaily.com/rust-to-rechargeable-how-seawater-and-scrap-metal-are-changing-energy-storage/

Scientists Unveil AI That Learns Without Human Labels – A Major Leap Toward True Intelligence!

This is what living on the cusp of the technological singularity is like:

https://scitechdaily.com/scientists-unveil-ai-that-learns-without-human-labels-a-major-leap-toward-true-intelligence/

Breakthrough Discovery: Scientists Restore Key Alzheimer’s Pathway

This is exciting:

They found that in the brains of people affected by Alzheimer’s disease or who carried the APOE4 gene putting them at higher risk for the disease, ABCA1 increased, but became trapped in a part of the cell that typically clears waste. That change was linked to a rise in a modified form of cholesterol known as oxysterol. Lowering oxysterol, in both animal models and human stem cells, freed the trapped ABCA1 and restored the pathway to its healthy state.

https://scitechdaily.com/breakthrough-discovery-scientists-restore-key-alzheimers-pathway/

New AI Just Beat DeepSeek With Almost No Effort! (This Shouldn't Be Possible!)

AI is only accelerating:

https://www.youtube.com/watch?v=KuVN6PksVig

Sunday, February 16, 2025

Scientists Discover Mouth Bacteria Linked to Increased Alzheimer’s Risk

Individuals who had large numbers of the bacteria groups Neisseria and Haemophilus had better memory, attention, and ability to do complex tasks. These people also had higher levels of nitrite in their mouths.

On the other hand, greater levels of the bacteria, Porphyromonas, was more common in individuals with memory problems. Whereas the bacterial group Prevotella, was linked to low nitrite, which the researchers predict could in turn could mean poorer brain health and was more common in people who carry the Alzheimer’s Disease risk gene, APOE4.

https://scitechdaily.com/scientists-discover-mouth-bacteria-linked-to-increased-alzheimers-risk/

Scientists Just Made Cancer Radiation Therapy Smarter, Safer, and More Precise

https://scitechdaily.com/scientists-just-made-cancer-radiation-therapy-smarter-safer-and-more-precise/

Legions of Robots UNLEASHED in 2025... Robotic Era BEGINS.

The robots we have to look forward to:

https://www.youtube.com/watch?v=mKqoTiXkXmQ

Friday, February 14, 2025

OpenAI: The Age of AI Is Here!

Generalists beat specialists at their own game:

https://youtu.be/97kQRYwL3P0?si=TotyGCbasCQFUgS-

New Humanoid Robot HMND 01 AI Learning To Beat Tesla Bot With This (PRICE + MENTEEBOT V3)

Love seeing these robots advancing, especially when they are not from Tesla:

https://youtu.be/2vLRnjgz7WQ?si=HdxzDrmsPA1to6ry

Could We Be Fighting Alzheimer’s Wrong? New Research Suggests a Different Approach

https://scitechdaily.com/could-we-be-fighting-alzheimers-wrong-new-research-suggests-a-different-approach/

Scientists Just Unlocked a New Way to Supercharge Wireless Speeds With Graphene

https://scitechdaily.com/scientists-just-unlocked-a-new-way-to-supercharge-wireless-speeds-with-graphene/

Scientists Just Built a CO2-Eating Machine That Runs on Sunlight

https://scitechdaily.com/scientists-just-built-a-co2-eating-machine-that-runs-on-sunlight/

Scaling Up: How Increasing Inputs Has Made Artificial Intelligence More Capable

A good way to see the exponential progress of AI:

https://singularityhub.com/2025/02/11/scaling-up-how-increasing-inputs-has-made-artificial-intelligence-more-capable/

Sunday, February 2, 2025

DeepSeek R1 Cloned for $30?! PhD Student STUNNING Discovery

AI reasoning! 

I like the idea of many tiny, inexpensive, hyper-focused models. Perhaps less likely to go rogue? Or might that just encourage swarm AI? Just very interesting…  

https://youtu.be/e659KrxxN5w?si=uKLozfeXEBxMKtJr

Sunday, January 26, 2025

SMART Tokamak Ignites Fusion Revolution With First Plasma

https://scitechdaily.com/smart-tokamak-ignites-fusion-revolution-with-first-plasma/

Scientists Discover Promising Molecule That Restores Cognitive Function in Early Alzheimer’s

"After testing the effect of the drug WIN55.212-2, which interacts with cannabinoid receptors, on rodents in the early stages of the disease, the team found “that they behaved in the same way as those without brain damage: they learned and remembered spatial orientation in the same way,” explained Marta Moreno. “You could say that in some way the drug reversed the damage or protected the brain.”"

https://scitechdaily.com/scientists-discover-promising-molecule-that-restores-cognitive-function-in-early-alzheimers/

Scientists Have Proven It’s Possible to Bring a Dead Brain ‘Back to Life’—But There’s a Catch

So it looks like we're on the way to creating Frankenstein's monster or perhaps a "brain in a jar" that can be fed sensory perception of the real or a virtual world:

https://www.prevention.com/life/a63497934/brain-reanimation/

Cutting-edge technology: AI robots made in Germany

Germany is finally stepping into the game, which it really should, considering its engineering and manufacturing prowess:

https://www.youtube.com/watch?v=s3NmYL__-KA

Monday, January 20, 2025

Unitree G1 Bionic: Agile Upgrade

Unitree is ugly and it’s Chinese, but it costs only $16,000 and can actually run over the same hilly, rough terrain Optimus can only navigate walking: 

https://www.youtube.com/watch?v=CIkdq7Zf4Zw

Sunday, January 19, 2025

Artificial Super Intelligence (ASI) is imminent - Cognitive Hyper Abundance is coming

Oh yeah, we are indeed on that wild ride up the dogleg to the technological singularity. So this is what it feels like. I’ve wondered about that for decades now…and it’s here, right on schedule.

https://youtu.be/-J9xJDS1T7k?si=lgK1-thNW3YlwPED

DOE Scientists Uncover Massive Potential: Floating Solar Panels Could Power 100 Million Homes

https://scitechdaily.com/doe-scientists-uncover-massive-potential-floating-solar-panels-could-power-100-million-homes/

Researchers STUNNED As AI Improves ITSELF Towards Superintelligence "OpenAI have 'broken out'..."

Once AI can improve on its own design, there’s really no stopping the run up to true ASI:

https://www.youtube.com/watch?v=Zy8tKHVSJfo&feature=youtu.be

Longevity Breakthrough: Scientists Restore “Youthful” Enzyme Activity To Combat Aging

https://scitechdaily.com/longevity-breakthrough-scientists-restore-youthful-enzyme-activity-to-combat-aging/

From Cold Sores to Memory Loss: The Herpes-Alzheimer’s Connection Unveiled

Oh, terrific:

https://scitechdaily.com/from-cold-sores-to-memory-loss-the-herpes-alzheimers-connection-unveiled/

100x Faster: Light-Powered Memory That’s Revolutionizing Computing

https://scitechdaily.com/100x-faster-light-powered-memory-thats-revolutionizing-computing/

OpenAI Just Won Gold on the 2025 International Math Olympiad — BIGGEST AI NEWS ALL YEAR!

Math is the basis of every science. Solve math and you can accomplish almost anything. https://youtu.be/PktE7KNg8WA?si=6fclUIXcEDi66-fq